HEALTH AND HUMAN SERVICES, DEPARTMENT OF › NATIONAL INSTITUTES OF HEALTH › ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Response deadline: Oct 7, 2026; 2:00 PM UTC-04:00
Set-aside: Not stated
Notice type: Solicitation
Posted on SAM.gov: Sep 17, 2026; Archives Oct 22, 2026

Description

The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth. ARPA-H anticipates multiple Other Transaction awards resulting from this announcement. Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165 Amendment 01 – 17 September 2026: This amendment includes updated hyperlinks and information on the updated Solutions summary portal.

From SAM.gov’s daily data file, as published on Oct 22, 2026 (UTC). SAM.gov’s latest daily file no longer lists this notice.

Contacts

COSMOS Team · primary
[email protected]

Attachments

BidLookup records the links this notice gives. It has not downloaded or checked the files.

Record dates

Posted on SAM.gov: Sep 17, 2026: The agency’s publication date, as SAM.gov states it.
First recorded by BidLookup: Sep 20, 2026: The UTC day of the first read of SAM.gov’s listings that stored this notice.
Last confirmed: Sep 20, 2026: The UTC day of the latest read that still listed this notice. It does not mean the notice is unchanged or still open on SAM.gov now, and it is not the index’s last-read time.
Description as published: Oct 22, 2026 (UTC): The date of the daily data file this text came from.

Published by the agency on SAM.gov as notice a0daed815bbc41289b0477bf9520ab1b. What these dates mean

Record