Sole Source Bioconscientia

The successful execution of this work requires an integrated research environment capable of combining artificial intelligence (AI)-driven protein engineering, high-throughput automated bioprocessing, and cell-free expression systems. Specifically, the contractor must have immediate, proven expertise in: Engineering UV-B-responsive genetic circuits and complex two-component systems (TCS). Developing AI-guided Rubisco variants and scaling up automated fermentation. Pioneering affinity-based separation platforms specifically targeted at REE recovery from e-waste and processed magnets. Advanced bio-electronic material fabrication (e.g., genetically encoded conductive protein nanowires and carbon quantum dot functionalization). No other source possesses the synergistic combination of specialized personnel, advanced laboratory infrastructure, and concurrent expertise across these disparate domains (biological CO2 assimilation, bio-electronics, and REE chromatography) required to meet the Government's stringent timelines and technical objectives without unacceptable delays or duplication of cost. The Government intends to procure from only one source under the authority RFO 6.103-1 Only One Responsible Source and No Other Supplies or Services Will Satisfy Agency Requirements. This Notice of Intent is for information purposes only. This is not a request for quote. A solicitation will not be issued. All responsible sources may submit a capability statement to [email protected], Subject Line "Sole Source Bioconsciencia" not later than the date indicated in this notice. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Verbal responses are not acceptable.